Connection | Profiles RNS

Search Result Details

Back to Search Results

This page shows the details of why an item matched the keywords from your search.

Search Results

WARGO, JENNIFER

One or more keywords matched the following items that are connected to WARGO, JENNIFER

Item Type	Name
Concept	Drug Resistance, Neoplasm
Academic Article	Systematic identification of signaling pathways with potential to confer anticancer drug resistance.
Academic Article	RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E).
Academic Article	MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition.
Academic Article	COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Academic Article	Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion.
Academic Article	Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.
Academic Article	A melanocyte lineage program confers resistance to MAP kinase pathway inhibition.
Academic Article	The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition.
Academic Article	Elucidating distinct roles for NF1 in melanomagenesis.
Academic Article	BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition.
Academic Article	PDGFRa up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation.
Academic Article	A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors.
Academic Article	Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics.
Academic Article	Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1a and oxidative phosphorylation in melanoma.
Academic Article	EPHA2 is a mediator of vemurafenib resistance and a novel therapeutic target in melanoma.
Academic Article	The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies.
Academic Article	Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma.
Academic Article	MITF Modulates Therapeutic Resistance through EGFR Signaling.
Academic Article	Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.
Academic Article	Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment.
Academic Article	Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.
Academic Article	Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy.
Academic Article	sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance.
Academic Article	The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression.
Academic Article	Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.
Academic Article	Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma.
Academic Article	Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial.
Academic Article	Loss of IFN-? Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.
Academic Article	Interaction of molecular alterations with immune response in melanoma.
Academic Article	Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.
Academic Article	Hallmarks of response to immune checkpoint blockade.
Academic Article	Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma.
Academic Article	Tumor-associated B-cells induce tumor heterogeneity and therapy resistance.
Academic Article	Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine.
Academic Article	A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling.
Academic Article	PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance.
Academic Article	Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade.
Academic Article	Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy.
Academic Article	9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy.
Academic Article	Hallmarks of response, resistance, and toxicity to immune checkpoint blockade.
Academic Article	Targeting PD-L2-RGMb overcomes microbiome-related immunotherapy resistance.
Academic Article	Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells.

Search Criteria

Drug Resistance Neoplasm